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1

pH-Responsive Nanometric Polydiacetylenic Micelles Allow for Efficient Intracellular siRNA Delivery

Ripoll, Manon, Neuberg, Patrick, Kichler, Antoine, Tounsi, Nassera, Wagner, Alain, Remy, Jean-Serge

Journal:

ACS Applied Materials & Interfaces

Year:

2016

Language:

english

File:

PDF, 680 KB

english, 2016

2

Gene Transfer with a Series of Lipophilic DNA-Binding Molecules

Remy, Jean-Serge, Sirlin, Claude, Vierling, Pierre, Behr, Jean-Paul

Journal:

Bioconjugate Chemistry

Year:

1994

Language:

english

File:

PDF, 1.59 MB

english, 1994

3

From solution to in-cell study of the chemical reactivity of acid sensitive functional groups: a rational approach towards improved cleavable linker for biospecific endosomal release

Wagner, Alain, Jacques, Sylvain A, Leriche, Geoffray, Mosser, Michel, Nothisen, Marc, Muller, Christian D., Remy, Jean-Serge

Journal:

Organic & Biomolecular Chemistry

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

4

Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI)

Patrick Erbacher, Thierry Bettinger, Pascale Belguise-Valladier, Shaomin Zou, Jean-Luc Coll, Jean-Paul Behr, Jean-Serge Remy

Journal:

The Journal of Gene Medicine

Year:

1999

Language:

english

File:

PDF, 779 KB

english, 1999

5

Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse

Shao-Min Zou, Patrick Erbacher, Jean-Serge Remy, Jean-Paul Behr

Journal:

The Journal of Gene Medicine

Year:

2000

Language:

english

File:

PDF, 263 KB

english, 2000

6

Effective polyethylenimine-mediated gene transfer into human endothelial cells

Violeta Zaric, Denis Weltin, Patrick Erbacher, Jean-Serge Remy, Jean-Paul Behr, Dominique Stephan

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 199 KB

english, 2004

7

A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin

Idit Kopatz, Jean-Serge Remy, Jean-Paul Behr

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 303 KB

english, 2004

8

MMT, Npeoc-protected spermine, a valuable synthon for the solid phase synthesis of oligonucleotide oligospermine conjugates via guanidine linkers

Phanélie Perche, Mitsuharu Kotera, Jean-Serge Remy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 362 KB

english, 2011

9

Lipospermine-mediated gene transfer technique into murine cultured cortical cells

Brigitte Sola, Cathy Staedel, Jean-Serge Remy, Amina Bahr, Jean-Paul Behr

Journal:

Journal of Neuroscience Methods

Year:

1997

Language:

english

File:

PDF, 266 KB

english, 1997

10

Chitosan-Based Vector/DNA Complexes for Gene Delivery: Biophysical Characteristics and Transfection Ability

Patrick Erbacher, Shaomin Zou, Thierry Bettinger, Anne-Marie Steffan, Jean-Serge Remy

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 1.52 MB

1998

11

Gene transfer with lipospermines and polyethylenimines

Jean-Serge Remy, Bassima Abdallah, Maria Antonietta Zanta, Otmane Boussif, Jean-Paul Behr, Barbara Demeneix

Journal:

Advanced Drug Delivery Reviews

Year:

1998

Language:

english

File:

PDF, 1.88 MB

english, 1998

12

Oligonucleotide−Oligospermine Conjugates (Zip Nucleic Acids): A Convenient Means of Finely Tuning Hybridization Temperatures

Noir, Régis, Kotera, Mitsuharu, Pons, Bénédicte, Remy, Jean-Serge, Behr, Jean-Paul

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 334 KB

english, 2008

13

Gene delivery with polycationic fullerene hexakis-adducts

Sigwalt, David, Holler, Michel, Iehl, Julien, Nierengarten, Jean-François, Nothisen, Marc, Morin, Emmanuelle, Remy, Jean-Serge

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 2.62 MB

english, 2011

14

Convenient Polymer-Supported Synthetic Route to Heterobifunctional Polyethylene Glycols

Bettinger, Thierry, Remy, Jean-Serge, Erbacher, Patrick, Behr, Jean-Paul

Journal:

Bioconjugate Chemistry

Year:

1998

Language:

english

File:

PDF, 74 KB

english, 1998

15

Genuine DNA/polyethylenimine (PEI) Complexes Improve Transfection Properties and Cell Survival

Erbacher, Patrick, Bettinger, Thierry, Brion, Emmanuel, Coll, Jean-Luc, Plank, Christian, Behr, Jean-Paul, Remy, Jean-Serge

Journal:

Journal of Drug Targeting

Year:

2004

Language:

english

File:

PDF, 776 KB

english, 2004

16

Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin

Perche, Phanélie, Nothisen, Marc, Bagilet, Jérémy, Behr, Jean-Paul, Kotera, Mitsuharu, Remy, Jean-Serge

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 843 KB

english, 2013

17

Proton Sponge Trick for pH-Sensitive Disassembly of Polyethylenimine-Based siRNA Delivery Systems

Creusat, Gaelle, Rinaldi, Anne-Sophie, Weiss, Etienne, Elbaghdadi, Rkia, Remy, Jean-Serge, Mulherkar, Rita, Zuber, Guy

Journal:

Bioconjugate Chemistry

Year:

2010

Language:

english

File:

PDF, 3.58 MB

english, 2010

18

Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles

Koniev, Oleksandr, Leriche, Geoffray, Nothisen, Marc, Remy, Jean-Serge, Strub, Jean-Marc, Schaeffer-Reiss, Christine, Van Dorsselaer, Alain, Baati, Rachid, Wagner, Alain

Journal:

Bioconjugate Chemistry

Year:

2014

Language:

english

File:

PDF, 338 KB

english, 2014

19

Dimerizable Cationic Detergents with a Low cmc Condense Plasmid DNA into Nanometric Particles and Transfect Cells in Culture

Dauty, Emmanuel, Remy, Jean-Serge, Blessing, Thomas, Behr, Jean-Paul

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 223 KB

english, 2001

20

Intracellular Delivery of Nanometric DNA Particles via the Folate Receptor

Dauty, Emmanuel, Remy, Jean-Serge, Zuber, Guy, Behr, Jean-Paul

Journal:

Bioconjugate Chemistry

Year:

2002

Language:

english

File:

PDF, 302 KB

english, 2002

21

Monomolecular Collapse of Plasmid DNA into Stable Virus-Like Particles

Thomas Blessing, Jean-Serge Remy and Jean-Paul Behr

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.30 MB

english, 1998

22

Size Reduction of Galactosylated PEI/DNA Complexes Improves Lectin-Mediated Gene Transfer into Hepatocytes

Bettinger, Thierry, Remy, Jean-Serge, Erbacher, Patrick

Journal:

Bioconjugate Chemistry

Year:

1999

Language:

english

File:

PDF, 80 KB

english, 1999

23

Cationic Polydiacetylene Micelles for Gene Delivery

Morin, Emmanuelle, Nothisen, Marc, Wagner, Alain, Remy, Jean-Serge

Journal:

Bioconjugate Chemistry

Year:

2011

Language:

english

File:

PDF, 3.40 MB

english, 2011

24

Controlled Template-Assisted Assembly of Plasmid DNA into Nanometric Particles with High DNA Concentration

Ouyang, Ming, Remy, Jean-Serge, Szoka, Francis C.

Journal:

Bioconjugate Chemistry

Year:

2000

Language:

english

File:

PDF, 256 KB

english, 2000

25

Fine-Tuning the Morphology of Self-Assembled Nanostructures of Propargyl Ammonium-Based Amphiphiles

Morin, Emmanuelle, Guenet, Jean-Michel, Díaz, David D., Remy, Jean-Serge, Wagner, Alain

Journal:

Journal of Physical Chemistry B

Year:

2010

Language:

english

File:

PDF, 1.99 MB

english, 2010

26

Cationic siRNAs Provide Carrier-Free Gene Silencing in Animal Cells

Nothisen, Marc, Kotera, Mitsuharu, Voirin, Emilie, Remy, Jean-Serge, Behr, Jean-Paul

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

27

Template Oligomerization of DNA-Bound Cations Produces Calibrated Nanometric Particles

Blessing, Thomas, Remy, Jean-Serge, Behr, Jean-Paul

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 49 KB

english, 1998

28

Dynamic Micelles of Mannoside Glycolipids are more Efficient than Polymers for Inhibiting HIV-1 trans -Infection

Schaeffer, Evelyne, Dehuyser, Laure, Sigwalt, David, Flacher, Vincent, Bernacchi, Serena, Chaloin, Olivier, Remy, Jean-Serge, Mueller, Christopher G., Baati, Rachid, Wagner, Alain

Journal:

Bioconjugate Chemistry

Year:

2013

Language:

english

File:

PDF, 4.23 MB

english, 2013

29

Dimerizable Detergents as Gene Transfer Vectors

Blessing, Thomas, Dauty, Emmanuel, Remy, Jean-Serge, Behr, Jean-Paul

Journal:

Journal of Liposome Research

Year:

2000

Language:

english

File:

PDF, 463 KB

english, 2000

30

Polyethylenimine but Not Cationic Lipid Improves Antisense Activity of 3′-Capped Phosphodiester Oligonucleotides

DHEUR, SONIA, DIAS, NATHALIE, VAN AERSCHOT, ARTHUR, HERDEWIJN, PIET, BETTINGER, THIERRY, RÉMY, JEAN-SERGE, HÉLÈNE, CLAUDE, SAISON-BEHMOARAS, E. TULA

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1999

Language:

english

File:

PDF, 8.31 MB

english, 1999

31

Gene Transfer Optimization with Lipospermine-Coated DNA

BARTHEL, FABRICE, REMY, JEAN-SERGE, LOEFFLER, JEAN-PHILIPPE, BEHR, JEAN-PAUL

Journal:

DNA and Cell Biology

Year:

1993

Language:

english

File:

PDF, 2.82 MB

english, 1993

32

Polycationic Pillar[5]arene Derivatives: Interaction with DNA and Biological Applications

Nierengarten, Iwona, Nothisen, Marc, Sigwalt, David, Biellmann, Thomas, Holler, Michel, Remy, Jean-Serge, Nierengarten, Jean-François

Journal:

Chemistry - A European Journal

Year:

2013

Language:

english

File:

PDF, 844 KB

english, 2013

33

Targeted transfection of human hepatoma cells with a combination of lipospermine and neo-galactolipids

Kichler, Antoine, Remy, Jean-Serge, Behr, Jean-Paul, Schuber, Francis

Journal:

Journal of Liposome Research

Year:

1995

Language:

english

File:

PDF, 547 KB

english, 1995

34

Photopolymerized micelles of diacetylene amphiphile: physical characterization and cell delivery properties

Neuberg, Patrick, Perino, Aurélia, Morin-Picardat, Emmanuelle, Anton, Nicolas, Darwich, Zeinab, Weltin, Denis, Mely, Yves, Klymchenko, Andrey S., Remy, Jean-Serge, Wagner, Alain

Journal:

Chemical Communications

Year:

2015

Language:

english

File:

PDF, 899 KB

english, 2015

35

Spiro Diorthoester (SpiDo), a Human Plasma Stable Acid-Sensitive Cleavable Linker for Lysosomal Release

Leriche, Geoffray, Nothisen, Marc, Baumlin, Nadège, Muller, Christian D., Bagnard, Dominique, Remy, Jean-Serge, Jacques, Sylvain A., Wagner, Alain

Journal:

Bioconjugate Chemistry

Year:

2015

Language:

english

File:

PDF, 651 KB

english, 2015

36

High-Efficiency Transfection of Primary Human Keratinocytes with Positively Charged Lipopolyamine: DNA Complexes.

Staedel, Cathy, Remy, Jean-Serge, Hua, Zhongxue, Broker, Thomas R., Chow, Louise T., Behr, Jean-Paul

Journal:

The Journal of Investigative Dermatology

Year:

1994

File:

PDF, 2.06 MB

1994

37

Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation

Flacher, Vincent, Neuberg, Patrick, Point, Floriane, Daubeuf, François, Muller, Quentin, Sigwalt, David, Fauny, Jean-Daniel, Remy, Jean-Serge, Frossard, Nelly, Wagner, Alain, Mueller, Christopher G.,

Journal:

ACS Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

38

Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection

Muñoz, Antonio, Sigwalt, David, Illescas, Beatriz M., Luczkowiak, Joanna, Rodríguez-Pérez, Laura, Nierengarten, Iwona, Holler, Michel, Remy, Jean-Serge, Buffet, Kevin, Vincent, Stéphane P., Rojo, Javi

Journal:

Nature Chemistry

Year:

2015

Language:

english

File:

PDF, 3.73 MB

english, 2015

39

Targeted Gene Transfer into Hepatoma Cells with Lipopolyamine-Condensed DNA Particles Presenting Galactose Ligands: A Stage Toward Artificial Viruses

Jean-Serge Remy, Antoine Kichler, Vyatcheslav Mordvinov, Francis Schuber and Jean-Paul Behr

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.00 MB

english, 1995

40

Gene Transfer with Multivalent Synthetic Vectors

Remy, Jean-Serge, Behr, Jean-Paul

Journal:

Journal of Liposome Research

Year:

1996

Language:

english

File:

PDF, 669 KB

english, 1996

41

Comments

Remy, Jean-Serge

Journal:

Journal of Liposome Research

Year:

1996

Language:

english

File:

PDF, 251 KB

english, 1996

42

Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing

Nothisen, Marc, Bagilet, Jérémy, Behr, Jean-Paul, Remy, Jean-Serge, Kotera, Mitsuharu

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 673 KB

english, 2016

43

Synthesis and Evaluation as a Gene Transfer Agent of a 1,2-Dimyristoyl- sn -glycero-3-pentalysine Salt

Weibel, Jean-Marc, Kichler, Antoine, Remy, Jean-Serge, Gaiddon, Christian, Loeffler, Jean-Philippe, Duportail, Guy, Heissler, Denis

Journal:

Chemistry Letters

Year:

1995

File:

PDF, 361 KB

1995

44

Preparation of poly(ethylene imine) derivatives with precisely controlled molecular weight

Landa, Matthieu, Kotera, Mitsuharu, Remy, Jean-Serge, Badi, Nezha

Journal:

European Polymer Journal

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

45

Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids

Nothisen, Marc, Perche-Létuvée, Phanélie, Behr, Jean-Paul, Remy, Jean-Serge, Kotera, Mitsuharu

Journal:

Molecular Therapy — Nucleic Acids

Year:

2018

Language:

english

File:

PDF, 2.29 MB

english, 2018

46

Synthesis and Evaluation of Antitumor Alkylphospholipid Prodrugs

Gaillard, Boris, Remy, Jean-Serge, Pons, FranÃ§oise, Lebeau, Luc

Journal:

Pharmaceutical Research

Year:

2020

File:

PDF, 1.37 MB

2020